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Sally Mohammed Ibrahim El-Hefnawy

PROFESSIONAL SUMMARY
  • 2006- 2007: General Practitioner, Depts. Of Surgery, Medicine, Pediatrics, OB/GYN, and Aneathesia, Menoufia University Hospitals.
  • March till June 2007: General Practitioner, Ministry of Health Hospitals- Menoufia Governorate- Egypt.
  • 2008- 2010: Demonstrator of Clinical Biochemistry; Medical Biochemistry Department – Faculty of Medicine – Menoufia University- Egypt.
  • 2010 – 2014: Assistant Lecturer of Clinical Biochemistry; Medical Biochemistry Department- Faculty of Medicine – Menoufia University- Egypt.
  • 2014 till 2019: Lecturer of Clinical Biochemistry; Medical Biochemistry Department- Faculty of Medicine – Menoufia University- Egypt.
  • 2019 till October 2022: Assistant professor of Clinical Biochemistry; Medical Biochemistry Department- Faculty of Medicine – Menoufia University- Egypt.
  • October 2022 till now: Assistant professor of Clinical Biochemistry; Medical Biochemistry Department- Faculty of Medicine – Merit University- Egypt (MUE).
EXPERIENCE
  1. Curriculum Planning: Participation in planning and specification of undergraduate and postgraduate Clinical Biochemistry courses at Faculty of Medicine -Menoufia University- Egypt
  2. Teaching Interests: Theoretical and practical teaching of Medical Biochemistry, and Molecular biology for:
    • Under graduate and postgraduate medical students at Faculty of Medicine – Menoufia University- Egypt
    • Under graduate medical students (special integrated medicine program) , Faculty of Medicine -Menoufia University- Egypt
    • Under graduate students of Faculty of Applied Health Science, Menoufia University- Egypt.
    • Postgraduate medical students (Master, diploma degrees) Faculty of Medicine- Menoufia University- Egypt.
  3. Seminars: Participation and attending the different seminars in the field of Clinical Biochemistry and Molecular Biology at Faculty of Medicine – Menoufia University- Egypt.
  4. Exams:
    • Sharing in the written and oral exams designing for assessment of the student understanding for both under graduate (main stream students) & postgraduate medical students at Faculty of Medicine, Menoufia University, Egypt
    • Sharing in the written exams designing for assessment of the student understanding for under graduate medical students (special integrated medicine program) , Faculty of Medicine -Menoufia University- Egypt
    • Sharing in the written and oral exams designing for assessment of the student understanding for under graduate students of Faculty of Applied Health Science, Menoufia University- Egypt.
    • Sharing in oral exams for assessment of under graduate students of Faculty of Pharmacy, Menoufia University- Egypt.
    • Sharing in oral exams for assessment of under graduate students of Faculty of Pharmacy, Kafr Elsheikh University- Egypt.
    • Sharing in oral exams for assessment of under graduate students of Faculty of Pharmacy, Elsadat University- Egypt.
    • Supervising and evaluating the graduation project for 4th year students of Faculty of Applied Health Science, Menoufia University- Egypt.
  5. Supervision of (51) thesis in Field of Biochemistry and molecular biology.
EDUCATION
  • 2005: Bachelor Degree (M. B. B.Ch.); General Medicine and Surgery (Excellent with honors) Faculty of Medicine- Menoufia University.
  • 2010: Master Degree (M. Sc.); Clinical Biochemistry (Excellent) – Faculty of Medicine- Menoufia University- Egypt. Thesis Titled; Elevated plasma Retinol Binding Protein (4) in human subjects with Type 2 diabetes mellitus
  • 2014: Doctorate Degree (M.D.); Clinical Biochemistry- Faculty of Medicine- Menoufia University- Egypt. Thesis titled; Evaluation of urinary Cytokeratin (20) mRNA as a diagnostic tool for bladder cancer.
  • 2019: Assistant professor at Medical Biochemistry & Molecular Biology Department, Faculty of Medicine- Menoufia University- Egypt.
PUBLICATIONS
  1. Plasma retinol binding protein (4) in patients with type 2 diabetes mellitus, Naglaa Mohammed Ghanayem1, Elsayed Saber Abou Elnour1, Ashraf Abd El- Raouf Dawood1, Mostafa El Najjar2 , Sally Mohammed Ibrahim El-Hefnawy1 J. Lab. Med. (2012) Vol. 38, No.2.
  2. Urinary cytokeratin 20 mRNA as a diagnostic tool for bladder cancer, Tarek F Abd El-Akim1, Maathir K El-Shafie1, Manal A Safan1, Ashraf A Dawood1, Sally M El-Hefnawy1, Abd El-Aleem M El-Deraee2 and Asmaa G Abdou3 (2013): Egyptian Society for Biochemistry and Molecular Biology.
  3. Urinary Biopyrrins: A New Marker of Oxidative Stress in Psoriasis (2016): Ola Ahmed  Bakry1,  Sally  El  Hefnawy2, Alaa Hassan Mariee1, Yara El Gendy1 Indian Journal of Dermatology; 61(2) : 169.
  4. The Association Between Interleukin-10 Gene Promoter Polymorphism and Insulin Resistance in Type 2 Diabetes Mellitus (2016): Sally Said Donia1, *, Eman Masoud Abd El Gayed2, Sally Mohamed El-Hefnawy2, Ahmed Ragheb3, American Journal of Clinical and Experimental Medicine; 4(3): 81-87
  5. Association of stem cell factor gene expression with severity and atopic state in patients with bronchial asthma (2017) : Safaa I. Tayel 1*, Sally M. El-Hefnway 1 , Eman M. Abd El Gayed 1 and Gehan A. Abdelaal 2, Respiratory Research 18:21
  6. Human Epidermal Growth Factor Receptor-3 mRNA Expression as a Prognostic Marker for Invasive Duct Carcinoma not Otherwise Specified (2017): Ghada Ezat Hammoda1, Sally Mohammed El-Hefnawy1, Asmaa gaber abdou3, Rania abdallah abdallah3, Journal of Clinical and Diagnostic Research., Vol-11(2): 1-5.
  7. Transcription factor 21 gene polymorphism in patients with coronary artery disease (2017): Waleed Abdou Hamed1, Ghada E Hammouda2 Sally M El-Hefnawy2 Eman M Abd El-Gayed2, Research Reports in Clinical Cardiology -8: 13-18
  8. Bone mineral  density  in  children  with  idiopathic nephrotic  syndrome (2017): Ghada  Mohamed  El-Mashad 1,  Mahmoud  Ahmed  El-Hawy1, Sally  Mohamed  El-Hefnawy 2,  Sanaa  Mansour  Mohamed 1, J Pediatr (RIO J),: 93 (2) 142-147.
  9. HFE gene mutation and iron overload in Egyptian pediatric acute lymphoblastic leukemia survivors: a single-center study (2017):Farida H. El-Rashedi 1, Mahmoud A. El-Hawy 1, Sally M. El-Hefnawy2 & Mona M. Mohammed 1, HEMATOLOGY, Hematology 22 (7), 398-404‏
  10. Assessment of Obesity and Hepatic Late Adverse Effects in the Egyptian Survivors of Pediatric Acute Lymphoblastic Leukemia: a Single Center Study (2017), Farida H. El-Rashedy 1, Mahmoud A. El-Hawy1, Sally M. El Hefnawy2 and Mona M. Mohammed1, Mediterranean Journal  of  Hematology  and  Infectious  Diseases,; 9; e2017026
  11. Value of Soluble Transferrin Receptors and sTfR/log Ferritin in the Diagnosis of Iron Deficiency Accompanied by Acute Infection (2017): Fady M. El-Gendy1, Mahmoud A. El-Hawy1, Mohamed S. Rizk2, Sally M. El-Hefnawy2 & Mohamed Z. Mahmoud1, Indian Journal of Hematology and Blood Transfusion, 34: 104–109.
  12. Genetic Polymorphism of Angiotensin Converting Enzyme and Its Plasma Level as a Risk Factor in Patients with Chronic Kidney Disease (2017):Eman M Abd El Gayed1, Sally M. El- Hefnawy1, Khaled Ma Elzorkany2, J. Lab. Med. Vol. 42(3): 645 – 656
  13. Fat Mass and Obesity-Associated Gene Polymorphism rs9939609 in Childhood Obesity (2017): Sally M. El-Hefnway 1, Nevein M. Al-sheikh1, Nahla M. Said2. Arab. J. Lab. Med. Vol. 42, No. 3: 523 – 534.
  14. Mean platelet volume and serum uric acid in neonatal sepsis (2017) :Ghada M. El‑Mashad1, Hanan M. El‑Sayed1, Mohamed S. Rizk2, Sally M. El‑Hefnawy2, Tamer W. El‑Zayat1 Menoufia Med J 30:581–587
  15. Effect of zinc supplementation on serum zinc and leptin levels in children on regular hemodialysis (2018): Ghada M. El‑Mashad1, El‑Sayed I. El‑Gebally1, Sally M. El- Hefnawy2, Asmaa M. El‑Sayed Saad1 Menoufia Med J 31:664–670
  16. Evaluation of urinary vitamin D‑binding protein in type 1 diabetic children (2018) Maha Atef Tawfik1, Soheir Sayed Abou‑El Ellaa1, Sally Mohammed El‑Hefnawy2, Mai Abou‑El‑Nasser El‑Borai1 , Menoufia Med J, in press
  17. Leptin receptor gene (A/G) polymorphism rs1137101 and renal cell carcinoma (2018), Azza M. Abdu Allah1, Sally M. El- Hefnway1, Alshimaa M. Alhanafy2, Ahmed M. Zahran3 & Heba E. Kasem3, Mol. Cell Biochem. 448, (1–2): 137–144. DOI 10.1007/s11010-018-3320-1
  18. Plasma von Willebrand Factor and a Disintegrin and Metalloproteinase with Eight Thrombospondin‑type 1 Motif Levels in Hemodialysis Patients: Relation to Vascular Access Thrombosis, (2018) Khaled M. A. Elzorkany1, Belal A. M. Montaser2, Sally M. El‑Hefnawy3 , Indian Journal of Nephrology-IJN:28(4), 278-282
  19. Evaluation of the role of adrenomedullin in febrile neutropenia (2018). Fady M. El‑Gendy1, Mahmoud A. El‑Hawy1, Sally M. El‑Hefnawy2, Dina M. Adel Ahmed Shalaby1 Menoufia Med J 31:671–676
  20. Pyruvate Kinase Isoform M2 as a Diagnostic Tool for Renal Cell Carcinoma (2018): Ibrahim El Tantawy El Sayed*1, Sally Mohammed El-Hefnway2, Alshimaa Mahmoud Alhanafy3 and Khadiga Mohamed Sallam2 European Journal of Pharmaceutical and Medical Research. www.ejpmr.com
  1. Cholesterol 7-Alpha Hydroxylase Gene (CYP7A1) Promoter Polymorphism rs3808607 as a Risk Factor for Pulmonary Tuberculosis in Egypt (2018). Nevein M. Al-Sheikh1, Sally M. El-Hefnawy1, Ahlam A. El-Shetahy2. Meta Gene 16: 66–71.
  2. Metadherin mRNA Expression in Hepatocellular Carcinoma (2018). Nevein M. Al-Sheikh1, Sally M. El-Hefnawy1, Ahmed M. Abuamer 2, Ashraf G. Dala 3. The Egyptian Journal of Medical Human Genetic, 19: 391-397.
  3. Plasma Circular RNA (0054633) Expression as a Biomarker for Pre-diabetes and Type 2 Diabetes Mellitus (2018). Sally M. El-Hefnway1, Nevein M. Al-Sheikh1 , Heba E .Kasem2 , Fatma A. El-Esrigy3. Bull. Egypt. Soc. Physiol. Sci. 38(1):77-88.
  4. FimH Adhesin among Enterobacter spp. Isolates and its Relation to Biofilm Formation and Antimicrobial Resistance Pattern (2018), Mabrouk M Ghonaim1, Amira H Elkhyat1, Sally M El-Hefnawy 2, Elham A Hossam Eldeen1, Egyptian Journal of Medical Microbiology, Volume 27 / No.4 /: 45-53.
  5. Digeorge Syndrome Critical Region (5) as a tumor suppressor gene in hepatocellular carcinoma (2018): Asmaa mahmoud shukry el-banna1, Ghada ezzat hamoda 1, Sally Mohammed El-Hefnawy2 and Alshimaa mahmoud alhanafy3, j. lab. med. 43 (3) : 685 – 695
  6. Polymorphisms of Interleukin-1β and Cytotoxic T lymphocyte Associated Antigen-4 Genes in Systemic Lupus Erythematosus (2019): Hassan Elbanna M. Younes1, Mabrouk M. Ghonaim1, Amira H. Elkhyat1, Alaa A. Labeeb2, Sally M. El-Hefnawy3 and Amal M. Dawoud1, Egyptian Journal of Medical Microbiology, Volume 28 : 1-8
  7. Role of calgranulin C protein in psoriasis (2019): Mohamed A. Bashaa, Wafaa A. Shehataa, Sally M. El‑Hefnawy and Shimaa A. Ibrahim, Menoufia Med J, 32:250–254
  8. The Genetic Variants of IKZF1 Gene Linked with the Growing Risk of Childhood Acute Lymphoblastic Leukaemia (2019): Safaa I. Tayel , Sally M. El-Hefnway, Wafaa M. Abo-Elfotoh  and Rania S. El-zayat, Current Molecular Medicine, 19, 1-8
  9. Endothelin‑1 gene polymorphism in Egyptian patients with Vitiligo (2019): Mohammed A. Shoeib, Ola A. Bakry, Sally M. El‑Hefnawy, Douaa S. Alsaadany, Menoufia Medical Journal, 32:1019–1024
  10. Evaluation of urinary vitamin D‑binding protein in type 1 diabetic children (2019): Maha A. Tawfik, Soheir S. Abou‑El Ella, Sally M. El‑Hefnawy, Mai A. El‑Borai, Menoufia Medical Journal , 32:1064–1070
  11. The role of osteopontin in dermatological diseases (2019):Alaa H. Marea, Wafaa A. Shehata, Sally M. El‑Hefnawy, Amany M. Mohsen, Menoufia Medical Journal, 32:751–755.
  12. Assessment of blood level of vitamin C in children with bronchial asthma (2020): Fahima M. Hassan, Ahmed A. Khataba, Rania S. El‑Zayat, Sally M. El‑Hefnawy, Heba G. A. El‑Hameed, Menoufia Medical Journal, 33:179–185
  13. Simultaneous Assessment of MicroRNA 126 and 192 in Diabetic Nephropathy Patients and Their Relation with Urinary Albumin. Safaa I. Tayel, Amany A. Saleh, Sally M. El-Hefnway, Khaled M. Elzorkany, Ghada E. Elgarawany and Rasha I. Noreldin (2020): Curr Mol Med. doi: 10.2174/1566524019666191019103918
  14. Dysregulation of cell-free long non-coding RNAs (NEAT2, CTC-471J1.2 and lnc-DC) in Egyptian systemic lupus and lupus nephritis patients, Amany A.Saleh  Heba E.Kasem  EnasZahran Sally M.El-Hefnawy. (2020) Meta Gene https://doi.org/10.1016/j.mgene.2020.100665
  15. Prevalence of and mothers’ knowledge, attitude and practice towards glucose-6-phosphate dehydrogenase deficiency among neonates with jaundice: a cross-sectional study. Zeinab A Kasemy ,1 Wael A Bahbah,2 Sally M El Hefnawy,3 Safa H Alkalash4. BMJ Open 2020;10:e034079. doi:10.1136/bmjopen-2019-034079
  16. Chitinase 3-like 1 gene (T/C) polymorphism and serum YKL-40 levels in patients with hepatocellular carcinoma, (2020):  Amany A. Saleh,, Alshimaa M. Alhanafy, Osama Elbahr, Sally M. El-Hefnawy, Meta Gene. 24 : 100686
  17. Cell-free long non-coding RNAs (LY86-AS1 & HCG27_201and GAS5) as

biomarkers for pre-diabetes and type 2 DM in Egypt. (2020): Amany A. Saleh, Heba E. Kasem, Enas S. Zahran, Sally M. El-Hefnawy∗. Biochemistry and Biophysics Reports. 23:100770

  1. Determination of oxidative stress in vitiligo by measuring superoxide dismutase levels in vitiliginous skin (2020): Ola Bakry, Sally Elhefnawy, Eman Seliet, Mai A. Omar. Menoufia Medical Journal 2020, 33:262–266
  2. Interferon regulatory factor (5) Gene Variants (rs2004640) as Genetic Risk Factor for

          Systemic Lupus Erythematosus but not Lupus Nephritis in Egyptian adults (2021): Sally M. El-Hefnawy1 Rasha G. Mostafa2, Heba E. Kasem3, Enas S. Zahran3 and Sherein S. ELnaidany 1. Bulletine of Egyptian Society for physiological science. In press.

  1. Association of TIRAP (rs8177374) and MyD88 (rs6853) genetic polymorphisms with susceptibility to pulmonary tuberculosis and treatment response (2020): Sally M. El-Hefnawy,*, Rasha G. Mostafa, Zeinab A. Kasemy, Hanaa A. Eid, Eman I. Elgizawy, Thoria A. Omar, Sherin S. EL Naidany. Gene Reports 21: 100825.
  2. Impact of missense mutation (rs1990760) at interferon-induced helicase (1) gene on non-segmental vitiligo (2020): Sally Mohammed El-Hefnawy* , Alaa Hassan Maraee, Nermin Tayel, Walaa El-Shenawy, Sherin Sobhy El-Naidany, Wafaa Ahmed Shehata. Gene Reports 21 : 100888.
  3. ESR1 gene polymorphism (rs827421) as a potential genetic marker for constitutional delay of growth and puberty in Egyptian adolescents (2021): Sally M. El-Hefnawy,*, Shimaa K. Zewain, Zeinab A. Kasemy, Wafaa A. Shehata, Shaimaa A. Hassanein, Mohamed Z. Nooh, Sherin S. EL Naidany. Steroids 166: 108778.
  4. Biochemical and molecular study on serum miRNA-16a and miRNA- 451 as neonatal sepsis biomarkers (2021): Sally M. El-Hefnawy*, Rasha G. Mostafa, Rania S. El zayat, Esraa M. Elfeshawy, Hamed M. Abd El-bari, Manal Abd El-Monem Ellaithy. Biochemistry and Biophysics Reports 25:100915.
  5. Uncoupling protein 2 and dynamin-related protein 1 mRNA expressions as genetic markers for plaque psoriasis (2021): Wafaa A. Shehata1, Mostafa A. Hammam1, Rasha S. Enany2, Sally M. El-Hefnawy3, and Shimaa Abdelsattar4, International Journal of Dermatology. doi: 10.1111/ijd.15788
  6. Simultaneous genotyping of rs3752462 and rs4821480 at non-muscle myosin-9 in diabetic nephropathy (2021): Sally M. El-Hefnawy a,*, Hatem M. El sebay a, Mahmoud M. Emara b, Sara A. El derbaly a, Rania M.A. El shazly. Gene Reports 23 101199. https://doi.org/10.1016/j.genrep.2021.101199
  7. Circulating long noncoding RNA growth arrest-specific transcript 5 as a diagnostic marker and indicator of degree of severity in plaque psoriasis (2021): Wafaa Ahmed Shehata1, Alaa Maraee1, Manal Abd El Monem Ellaithy2, Nermin Tayel3, Asmaa Abo-Ghazala4, and Sally Mohammed El-Hefnawy2, International Journal of Dermatology. doi: 10.1111/ijd.15494
  8. Cord blood microRNA-376c and microRNA-1268a as biomarkers for neonatal hypoxic-ischaemic encephalopathy: a diagnostic accuracy study (2021): Dina Abdel Razek Midan ,1 Wael A Bahbah ,1 Doaa Ahmed Fayed,2 Ibrahim Tantawy,2 Hamed Mohamed Abdel Barry,2 Manal Abd El-Monem Ellaithy,3 Sally Mohammed Elhefnawy3. BMJ Paediatrics Open ;5:e001258. doi:10.1136/ bmjpo-2021-001258
  9. Mi-RNA-93 and Mi-RNA-152 in the Diagnosis of Type 2 Diabetes and Diabetic Retinopathy (2022): A. A. Saleh1, S.M. El-Hefnawy1*, Z. A. Kasemy2, A. A. Alhagaa3, M. Z. Nooh4 and E. S. Arafat1, British Journal of Biomedical Science. doi: 10.3389/bjbs.2021.10192
  10. COVID-19 susceptibility, severity, clinical outcome and Toll-like receptor (7) mRNA expression driven by TLR7 gene polymorphism (rs3853839) in middle-aged individuals without previous comorbidities, (2022): Sally M. El-Hefnawy a,*, Hanaa A. Eid b, Rasha G. Mostafa c, Shaimaa S. Soliman d, Thoria A. Omar e, Rania M. Azmy a. Gene Reports 27 :101612.  https://doi.org/10.1016/j.genrep.2022.101612.
  11. Potential impact of serpin peptidase inhibitor clade (A) member 4 SERPINA4 (rs2093266) and SERPINA5 (rs1955656) genetic variants on COVID-19 induced acute kidney injury (2022): Sally M. El-Hefnawy a,*, Zeinab A. Kasemy b, Hanaa A. Eid c, Ibrahim Elmadbouh a, Rasha G. Mostafa d, Thoria A. Omar e, Heba E. Kasem f, Eman M. Ghonaim g, Mohamed M. Ghonaim h, Amany A. Saleh a,i. Meta Gene 32 : 101023.
  12. Comparison of Fungal Fluorescent Staining and ITS rDNA PCR-based Sequencing with Conventional Methods for Diagnosis of Onychomycosis (2022): Amal F. Makled, Mabrouk M. Ghonaim1, Sahar A.M. Ali1, Sally Mohammed El-Hefnawy2, Mona Salah Sabal1* and Asmaa Mohammed Elbrolosy, J Pure Appl Microbiol | 16(2):1337-1349
  13. Dickkopf‑1 in ankylosing spondylitis patients and its relation to vertebral fractures and bone mineral density (2022):  Alaa A. Labeeb, Saga F. El Gazzar, Sally M. El‑Hefnawy, Laila M. Zedan, Menoufia Medical Journal, 35:172–176.
  14. Role of Toll‑like receptor 4 gene expression in psoriasis and its relation to disease activity (2022): Wafaa A. Shehata, Mostafa A. Hammam, Dalia S. Seif, Sherine S. Elsayed, Eman M. Abd El Maqsoud, Sally M. El‑Hefnawy. Menoufia Medical Journal, 35:418–423
  15. Farida H. El-Rashidy, Mohamed S. Abdullah, Sally M. El-Hefnawy, Basim A. El-Gazzar, Ahmed M. El-Hawwary & Mahmoud A. El-Hawy (2022) Endothelial nitric oxide synthase gene polymorphism (786T/C) in childhood acute lymphoblastic leukemia survivors, Expert Review of Hematology, DOI: 10.1080/17474086.2022.2112172
  16. Plasmodium falciparum Malaria Susceptibility and Severity: Influence of MyD88-Adaptor-Like Gene (rs8177374) Polymorphism; Amany I Ammar; Sally M El-Hefnawy; Somaia Shehab-Eldeen; Abdallah Essa; Sherin S ELnaidany; Rasha G Mostafa; Mortadah H Alsalman; Samar A El-Refai. Infection and Drug Resistance. DOI: 10.2147/IDR.S387463